Asiti ea lipoic ke coenzyme e teng ho mitochondria e nang le foromo ea molek'hule C8H14O2S2. E tšoana le livithamine 'me e ka felisa li-radicals tsa mahala tse bakang botsofali le maloetse a potlakileng. Lipoic acid e kena liseleng ka mor'a hore e kene ka mpeng 'meleng,' me e na le lintho tse peli tse qhibilihang ka mafura le tse qhibilihang ka metsing. Lipoic acid ke ea sehlopha sa metsoako ea livithamini tsa B. Ke ntlha ea kholo ea tomoso le likokoana-hloko tse ling. E bapala karolo ea coenzyme tsamaisong ea li-enzyme tse ngata mme e kenya letsoho ho decarboxylation ea oxidative ea pyruvate ho acetic acid le decarboxylation ea oxidative ea α-ketoglutarate ho succinic acid. Phetolelo ea mahareng.

Joalo ka coenzyme, lipoic acid e bapala karolo ho karabelo e 'meli ea bohlokoa ea oxidative decarboxylation, e leng, ho pyruvate dehydrogenase complex le α-ketoglutarate dehydrogenase complex, e leng se susumetsang tlhahiso le phetiso ea lihlopha tsa acyl. Lipoic acid e ka amohela sehlopha sa acyl le sehlopha sa acetyl sa pyruvate ho etsa tlamo ea thioester, ebe e fetisetsa sehlopha sa acetyl ho athomo ea sebabole ea molek'hule ea coenzyme A. Dihydrolipoamide e etsang sehlopha sa maiketsetso e ka ba oxidized ka dihydrolipoamide dehydrogenase (e hloka NAD +) ho tsosolosa lipoamide e nang le oxidized. Alpha-lipoic acid e na le sebopeho sa selikalikoe sa disulfide se nang le litho tse hlano se nang le matla a phahameng a elektronike, electrophilicity ea bohlokoa le bokhoni ba ho itšoara ka li-radicals tsa mahala. Ka hona, e na le thepa ea antioxidant 'me e na le mesebetsi e phahameng haholo ea tlhokomelo ea bophelo le boleng ba bongaka (joalo ka Anti-fatty sebete le ho theola litlamorao tsa plasma cholesterol).

Lipoic acid e sebelisoa haholo ho thibela tsoekere hore e se ke ea tlama protheine, ke hore, e na le phello ea "anti-glycation", ka hona e ka tsitsisa maemo a tsoekere ea mali habonolo. Ka hona, pele e ne e sebelisoa e le vithamine ho ntlafatsa metabolism 'me e nkiloe ke bakuli ba nang le lefu la sebete le lefu la tsoekere. . Ho matlafatsa ts'ebetso ea sebete Lipoic acid e na le ts'ebetso ea ho matlafatsa ts'ebetso ea sebete, ka hona e ne e sebelisoa hape e le antidote bakeng sa chefo ea lijo kapa chefo ea tšepe matsatsing a pele.

Hlōla Mokhathala Hobane lipoic acid e ka eketsa lebelo la metabolism ea matla 'me ea fetola lijo tse jeoang hore e be matla, e ka felisa mokhathala kapele le ho etsa hore' mele o se ke oa khathala. E Ntlafatsa 'Dementia' Karolo ea limolek'hule tsa lipoic acid e nyane haholo, ka hona ke e 'ngoe ea limatlafatsi tse' maloa tse ka fihlang bokong. E boetse e boloka tšebetso ea li-antioxidant bokong, hape e nkuoa e sebetsa haholo ho ntlafatsa 'dementia'.

Alpha lipoic acid ke antioxidant e matla. Hobane e qhibiliha ka metsing ebile e qhibiliha ka mafura. Sena se bolela hore e na le mefuta e mengata ea liphello, e fihlang seleng e 'ngoe le e' ngoe 'meleng ho sireletsa litho ho tsoa tšenyo e khōlō ea mahala. Joaloka antioxidant, alpha lipoic acid e ka fana ka tse ling tsa melemo e latelang: E ​​thusa ho qhaqha lintho tse chefo tse kang mercury le arsenic sebeteng ka ho eketsa tlhahiso ea glutathione. E khothalletsa ho tsosolosoa ha li-antioxidants tse ling, haholo-holo livithamini E, C, glutathione le coenzyme Q10. E bapala karolo ea bohlokoa ho fetoleng tsoekere hore e be matla. E thusa ho ntlafatsa tsebo ea nako e khuts'oane le ea nako e telele ea ho hopola.