The solvent extraction method for Chinese herbal medicines extracts is a method of dissolving active ingredients from the medicine material tissue based on the solubility properties of various parts of the Chinese herbal medicine in the solvent . The solvent e na le ho qhibiliha ho hoholo bakeng sa metsoako e sebetsang le ho fokotseha ho fokolang bakeng sa likarolo tse sa hlokeng ho qhibiliha.

Ha mokelikeli o eketsoa ho thepa e tala ea meriana ea litlama ea Sechaena (e lokelang ho hatelloa hantle), mokelikeli o kenella butle-butle ka seleng ka lerako la sele ka lebaka la ho hasana le osmosis, ho qhibiliha lintho tse qhibilihang ebe ho baka phapang ea mahloriso ka hare le ka ntle. sele. Ka lebaka leo, tharollo e tsepamisitsoeng ka seleng e tsoela pele ho hasana ka ntle, 'me solvent e tsoela pele ho kena liseleng tsa lisele tsa meriana. Ts'ebetso ena e khutlela morao le pele ka makhetlo a mangata ho fihlela mokoloko oa tharollo ka hare le ka ntle ho sele o fihla tekano e matla. Tharollo e tletseng e ea tlhotloa, 'me lihlapolli tse ncha li eketsoa ka makhetlo a mangata ho ntša likarolo tse hlokahalang ka ho feletseng kapa boholo.

Li-solvents tse sebelisoang hangata

1. Metsi:

- Likarolo: e bolokehile, e na le chelete e ngata, 'me ho bonolo ho e fumana, ke mokelikeli o sebelisoang haholo.

- Bophahamo ba ts'ebeliso: bo loketse lisebelisoa tse ngata tsa bongaka tsa China, haholo likarolo tse qhibilihang ka metsing tse kang polysaccharides, liprotheine, saponins, jj.

- Mefokolo: phello e mpe ea ho ntša likarolo tse ling tse qhibilihang ka mafura.

2. Ethanol:

- Likarolo: mahloriso a sebelisoang hangata ke 30% -95%, organic solvent, e ka qhala mefuta e fapaneng ea metsoako.

- Sekhahla sa ts'ebeliso: e sebelisoa haholo ho ntša flavonoids, phenols, glycosides, alkaloids, joalo-joalo.

- Mefokolo: e ka tukang, polokeho e lokela ho lebisoa tlhokomelo nakong ea ts'ebetso.

3. Methanol:

- Likarolo: polarity e kholo le solubility e matla.

- Bophahamo ba ts'ebeliso: e sebelisoa bakeng sa ho rala le ho arola likarolo tse itseng tsa limela.

- Mefokolo: e chefo, ha e tšoanelehe bakeng sa sehlahisoa sa ho qetela sa lijo le meriana.

4. Acetone:

- Likarolo: solubility e matla ebile ho bonolo ho e senya.

- Sebaka sa ts'ebeliso: se loketse ho ntšoa ha likarolo tse fapaneng, haholo likarolo tse qhibilihang ka mafura.

- Mefokolo: e chefo ebile e ka tuka, ka kopo ela hloko polokeho ha u sebelisa.

5. Ethyl acetate:

- Likarolo: polarity e mahareng, solubility e ntle.

- Sebaka sa ts'ebeliso: se loketse ho ntšoa ha metsoako ea polar e mahareng.

- Go tlhoka mesola: feto-fetoha, ka kopo ela hloko ventilation.v

Mekhoa e tloaelehileng ea ho ntša

1. Mokhoa oa ho ntša metsi:

- Mehato: Chesa 'me u belise meriana ka metsi, u e boloke nako e itseng, ebe u sefa moqomo.

- Kopo: E sebetsa ho lisebelisoa tse ngata tsa bongaka tsa China, haholo-holo likarolo tse qhibilihang ka metsing.

2. Mokhoa oa ho ntša joala:

- Mehato: Kopanya meriana le mokelikeli oa ethanol, soak kapa mocheso, 'me u sefa mokelikeli.

- Ts'ebeliso: E sebelisoa ho ntša likaroloana tsa tlhaho tse kang flavonoids, glycosides, le alkaloids.

3. Mokhoa oa ho ntša ultrasonic:

- Mehato: Sebelisa vibrate ea ultrasound ho potlakisa ho qhibiliha ha metsoako ea meriana ka solvent.

- Kopo: Ntlafatsa ts'ebetso ea ts'ebetso 'me e sebetsa ho li-solvents tse fapaneng le lisebelisoa tsa bongaka.

4. Mokhoa oa ho inela o batang:

- Mehato: Kenya lisebelisoa tsa moriana ka har'a solvent, e tlohele mocheso oa kamore ka nako e itseng, ebe u sefa sekhechana.

- Kopo: E sebetsa ha ho ntšoa likaroloana tse sa utloeleng mocheso.

5. Mokhoa oa ho ntša Reflux:

- Mehato: Chesa lisebelisoa tsa meriana le solvent hammoho bakeng sa reflux, e le hore solvent e fetohe mouoane 'me e tsitsinye ka ho tsoelang pele, ebe e ntša likaroloana tsa meriana ka potoloho.

- Kopo: E loketse lisebelisoa tsa bongaka tseo likarolo tsa tsona li leng thata ho li ntša.

6. Mokhoa oa ho ntša mokelikeli o phahameng haholo:

- Mehato: Sebelisa maro a joalo ka khabonetaeokosaete e maemong a holimo haholo joalo ka lihlapolli ho ntša metsoako e sebetsang linthong tsa meriana.

- Ts'ebeliso: E sebelisoa bakeng sa ho ntšoa ha likarolo tse sa utloeleng mocheso le tse nang le oxidized habonolo, 'me bohloeki ba ho ntša bo holimo.